Filmmaker Lynn Shelton, known for "Little Fires Everywhere" and "Humpday", has died. She was 54.

Shelton died on Friday in Los Angeles of a previously unidentified blood disorder. The news of her demise was shared by her longtime publicist Adam Kersh, reports hollywoodreporter.com.

She is also known for "Your Sister's Sister" and "My Effortless Brilliance".

Along with films, Shelton also was a prolific television director who worked on series including "Mad Men", "GLOW", "Little Fires Everywhere" and "The Morning Show".

On Twitter, Mark Duplass, a frequent collaborator, wrote: "We made so many things together. I wish we had made more. Her boundless creative energy and infectious spirit were unrivaled. She made me better. We butted heads, made up, laughed, pushed each other. Like family. What a deep loss."

Actress Reese Witherspoon, who worked with her on "Little Fires Everywhere", was heartbroken with the news.

"I'm so devastated to hear about Lynn Shelton's passing yesterday. I'm in complete shock that this vibrant, talented, and soulful filmmaker is no longer with us. Lynn was so passionate about our show, "Little Fires Everywhere", Witherspoon posted on Instagram along with a photograph of herself with the director.

The actress continued: "She said the book truly spoke to her, and that she longed to direct a show that spoke meaningfully about motherhood, sexuality, race, and class in America. And she did. She cared deeply about the WHOLE cast and crew, making sure we all felt heard, seen and appreciated. Lynn also shared so much of her life with us. Her love of her son, how motherhood changed her life, her life changing decisions that made her the woman she was. I feel so fortunate that I got to collaborate with Lynn on both aThe Morning Show' and aLittle Fires Everywhere'. Her spirit touched so many people in the filmmaking world. Her memory lives on in our vivid days together on set and in her wonderful films. Please watch her work and see her talent for yourself. #RestInPeaceLynn."

Shelton began her career as an editor, later moving on to make experimental short films. She made her feature debut as a director with 2006's "We Go Way Back". She was also approached for directing "Black Widow".